Best Fabrics for Medical Scrubs 2025 | B2B Guide
Discover the best fabrics for medical scrubs in 2025. Compare poly-spandex, cotton blends, rayon, and antimicrobial scrubs for durability, comfort, and wholesale sales.


Introduction: Why Fabric Choice Is Critical in 2025
Learn how Medlooms manufactures scrubs.
For retailers, clinics, and private-label scrub stores, selecting the right fabric determines:
Customer satisfaction and comfort
Durability and lifespan of scrubs
Brand reputation and repeat business
Profit margins and pricing strategy
Healthcare professionals want scrubs that are:
Stretchy and breathable
Wrinkle-resistant
Durable after 60+ washes
Comfortable for long shifts
Professional-looking
This guide will help you choose the best fabrics for medical scrubs, compare options, understand which fabrics sell best for retail and bulk orders, and give tips for fabric care to maximize lifespan.
1. What Fabric Are Medical Scrubs Made Of?
Most scrubs use one of these primary categories:
Polyester-Spandex Blends (Most Popular)
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Composition: ~92% Polyester, 8% Spandex
Features: Lightweight, stretchable, fade-resistant, wrinkle-free
Best For: Retailers, private-label brands, clinics needing durable, low-maintenance scrubs
Cotton-Polyester Blends (Traditional Choice)
Composition: 65% Polyester, 35% Cotton
Features: Soft, breathable, affordable, moderate durability
Best For: Bulk hospital orders, budget-conscious buyers
Rayon/Modal Blends (Premium Softness)
Composition: ~73% Rayon, 23% Polyester, 4% Spandex
Features: Luxury feel, excellent drape, high comfort
Best For: Boutique stores, premium private-label collections
Customize your boutique scrub collection.
100% Polyester Performance Fabrics
Features: Sweat-wicking, antimicrobial, cooling technology
Best For: Hospitals with hygiene protocols or surgical staff
2. Comparison Table: Fabric Features & Retail Suitability
3. Key Factors to Consider When Choosing Scrub Fabrics
Durability
Essential for bulk buyers; repeated washing should not shrink or fade the scrubs. Poly-Spandex blends are most durable.
Stretch & Comfort
4-way stretch fabrics reduce strain during long shifts. Rayon and spandex blends excel in comfort.
Breathability
Cotton or Rayon blends excel in hot climates. Essential for hospital staff working long hours.
Wrinkle Resistance
Polyester-rich fabrics stay crisp, reducing ironing and returns.
Price & Margins
Cotton-poly blends are low-cost; Poly-Spandex has higher perceived value. This affects retail positioning and profit.
Fabric Care Tips
Proper care maximizes lifespan and reduces shrinkage or pilling:
Wash scrubs in cold water to preserve color
Use mild detergents
Avoid high heat in dryers; air-dry when possible
Do not bleach unless fabric allows
Iron only if necessary (most poly-spandex blends are wrinkle-free)
Download scrub care guide.
4. Fabric Trends & What Sells Best in 2025
Polyester-Spandex (Most Popular)
Stretch + wrinkle-free = high customer satisfaction
Retailers report higher repeat sales with this fabric
Rayon/Modal (Premium Segment)
Soft touch and drape = boutique appeal
High margins, popular for private-label stores
Poly-Cotton Blends (Budget-Friendly)
Hospitals and bulk buyers prefer these
Affordable, easy to source, good margins
100% Polyester Tech (High Hygiene)
Sweat-wicking, antimicrobial, odor-resistant
Hospitals & surgical units prioritize hygiene features
See hospital case studies.
5. FAQs
Q1: Are polyester scrubs hot or uncomfortable?
A: Modern polyester blends with spandex or moisture-wicking technology are lightweight, breathable, and comfortable, even for long shifts.
Q2: Which scrub fabrics last the longest?
A: Poly-Spandex blends are the most durable, often lasting 600+ washes without significant fading or seam damage.
Q3: What is the ideal GSM for scrubs?
A: 150–170 GSM is optimal: structured but breathable for daily wear.
Q4: Are antimicrobial scrubs worth the investment?
A: Yes, especially in hospitals or surgical units. Polyester-based antimicrobial fabrics reduce bacterial growth and odor.
Q5: Cotton vs Polyester – which should I sell?
A: Cotton blends are soft and breathable; polyester blends are durable and wrinkle-free. For retail profit, poly-spandex is usually preferred.
Q6: How do I care for scrubs to make them last longer?
A: Wash in cold water, use mild detergent, air-dry if possible, avoid bleach, and iron only when necessary.
Q7: Which weave types are best for durability?
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A: Twill and poplin weaves offer the best balance of strength and comfort for scrubs.
Choosing the right fabric is critical for customer satisfaction, repeat sales, and profitability. Medlooms recommends:
Poly-Spandex (92/8) – durable, wrinkle-free, high retail demand
Poly-Cotton (65/35) – budget-friendly, breathable
Rayon/Modal Blends – premium soft feel for boutique collections
100% Polyester Tech – antimicrobial, moisture-wicking, hospital-grade
Get Samples & Wholesale Pricing Today:
Contact Medlooms to request fabric swatches, pricing, and private-label options. Make your store the destination for high-quality, durable, and professional scrubs.
